NMR
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DAVID WISHART (Project Leader) is a Professor in the Departments of Computing Science and Biological Sciences, and in the Faculty of Pharmacy at the University of Alberta. In 2003 he was cross-appointed as Director of Nanobiology and Senior Research Officer at the NRC's National Institute for Nanotechnology (NINT). He has co-founded two companies (Chenomx and BioTools) and serves as the Chief Scientific Officer for both. He is also the Director of the PENCE and Alberta Cancer Board bioinformatics core facilities, and the Director of the Canadian Bioinformatics Help Desk. Dr. Wishart held the CIHR Bristol-Myers Squibb chair in protein chemistry. He has won several awards including the AAAS young investigator prize and the Astra-Zeneca young investigator prize. Since 1990 Dr. Wishart has published more than 120 papers and book chapters, and presented more than 100 abstracts at scientific conferences. His discoveries concerning NMR chemical shifts in the early 1990's made him one of the most cited Canadian scientists of the past decade. Dr. Wishart will act as the project's Principal Investigator and will be active in characterizing the human metabolome via NMR, and in designing and testing key software. He will also be responsible for integrating the NMR, MS and microfluidics research projects and in working with clinical collaborators based at the University of Alberta and at the University of Calgary. |
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HANS VOGEL (Principal Investigator) is a Professor of Biochemistry and AHFMR Scientist in the Department of Biological Sciences at the University of Calgary. He is also the director of the Calgary Bio-NMR centre which houses numerous high field NMR instruments. Dr. Vogel's interests are in biomolecular NMR and the development of new NMR methods for characterizing biomolecules. After completing his PhD in Biochemistry at the University of Alberta in 1981 and studying in Sweden for 4 years, Dr. Vogel returned to Canada in 1985 to take up a position at the University of Calgary. Dr. Vogel has published more than 260 papers and book chapters covering a wide range of areas including biomolecular NMR, phosphorus NMR, and plant metabolism. He has won numerous awards including the Merck-Frosst Award (1994) from the Canadian Society of Biochemistry and Molecular Biology. Dr. Vogel will be involved in the metabolome characterization studies, NMR field dependency studies and in integrating MS and NMR data to improve the complementation between these technologies. |
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ALSU NAZYROVA (Postdoctoral Fellow) obtained her PhD degree in Organic Chemistry in 1990 from Kazan State University, Russia, and is currently working under Dr. Hans Vogel at the University of Calgary on expanding the Human Metabolome Database to include NMR spectra. She has over 15 years experience in organic and analytical chemistry. She has synthesized many heterocyclic organic compounds with interesting chemical and biological properties and NMR has been one of her primary tools in the characterization of novel compounds. Her research interests are also in the application of NMR spectroscopy to studies of isomerism and dynamics of organic compounds. |
