Metabolomics Toolbox

LIMS

Personnel

Bioinformatics

DAVID WISHART (Project Leader) is a Professor in the Departments of Computing Science and Biological Sciences, and in the Faculty of Pharmacy at the University of Alberta. In 2003 he was cross-appointed as Director of Nanobiology and Senior Research Officer at the NRC's National Institute for Nanotechnology (NINT). He has co-founded two companies (Chenomx and BioTools) and serves as the Chief Scientific Officer for both. He is also the Director of the PENCE and Alberta Cancer Board bioinformatics core facilities, and the Director of the Canadian Bioinformatics Help Desk. Dr. Wishart held the CIHR Bristol-Myers Squibb chair in protein chemistry. He has won several awards including the AAAS young investigator prize and the Astra-Zeneca young investigator prize. Since 1990 Dr. Wishart has published more than 120 papers and book chapters, and presented more than 100 abstracts at scientific conferences. His discoveries concerning NMR chemical shifts in the early 1990's made him one of the most cited Canadian scientists of the past decade. Dr. Wishart will act as the project's Principal Investigator and will be active in characterizing the human metabolome via NMR, and in designing and testing key software. He will also be responsible for integrating the NMR, MS and microfluidics research projects and in working with clinical collaborators based at the University of Alberta and at the University of Calgary.
RUSS GREINER (Principal Investigator) received his PhD in Computer Science from Stanford, worked first in academia then in industrial research. Dr. Greiner now works at the University of Alberta, where he is a Professor in Computing Science, and the founding Director of the Alberta Ingenuity Centre for Machine Learning (AICML), a multi-year, multi-million dollar research institute supported by the Alberta Ingenuity Fund. He is one of the founders of Chenomx Inc, and serves as the Chief Information Officer of PolyomX, Inc. He has received three recent patents and has over 90 refereed papers. Most of these are in the areas of machine learning and knowledge representation, especially probabilistic models such as Bayesian belief nets. Dr. Greiner will be involved in developing improved classification software for both the handheld CE-IMS instrument and the clinical NMR instruments, and in developing robust algorithms for rapid spectral/disease classification.
ROMAN EISNER (Researcher) finished his BSc in Computing Science at the University of Alberta in 2003, and has worked on research in Bioinformatics since 2001, mostly on research related to the Proteome Analyst project. He received his MSc in Computing Science in 2005 on Predicting Protein Function Using Machine-Learned Hierarchical Classifiers. He has experience in industry and is comfortable programming in Perl, Java, MySQL, Python, and C.
IAN FORSYTHE (Bioinformatician) has over 20 years experience in Biotechnology. He received his double AB in Molecular Biology and French from the University of California, Berkeley, and his MSc in Zoology from the University of British Columbia in 1997. He has worked for several prominent Biotechnology companies, including Genentech, Chiron, Syntex Research (now Roche Palo Alto), Gilead Sciences, ZymoGenetics, DNAX Research Institute, and Incyte Genomics. Ian comes to this project after several years of experience co-managing the Canadian Bioinformatics Help Desk at the University of Alberta. In 2006, Ian served as a member of the Canadian Proteomics Initiative Conference organizing committee. From 2006 to 2008, Ian served as project manager of the Human Metabolome Project.
CRAIG KNOX (Bioinformatician) is currently finishing his BSc in Computing Science with a specialization in bioinformatics at the University of Alberta. Although new to research, he has worked as a curator and programmer on the DrugBank and Human Metabolome projects. His computer skills include a strong knowledge of Perl, Java, C/C++, SQL, along with years of experience in web design. Craig's interests lie in developing tools to aid in drug research and design. In this regard he is continuing work on his Cytochrome P450 database and the associated machine learning tools used to predict Cytochrome P450 substrate binding.
SAVITA SHRIVASTAVA (Bioinformatician, Canadian Bioinformatics Help Desk) has a Master of Science Degree in Bioinformatics from Cologne University Bioinformatics Center (CUBIC), University of Cologne, Germany, and an MSc in Genetics from Bhopal University, India. She has more than four years of work experience in industry in the fields of bioinformatics, web development, and e-technology. Her computer skills include: Perl, Java, SQL, databases and web development. Savita's interest lies in applying biocomputational approaches and developing new computational tools to solve the underlying biological questions.
PETER TANG (System Analyst) received his BSc in Computing Science from the University of Alberta in 2003. Peter is currently working on the team as a System Analyst and has experience in Java, C/C++, Visual Basics, Flash, and MySQL. Peter is currently working on the SimCell project (http://wishart.biology.ualberta.ca/SimCell), a Biological Dynamic Cellular Automata (DCA) simulator.
NELSON YOUNG (Researcher) has over 10 years experience in computer programming. He received his BSc in Computer Engineering from the University of Alberta. Nelson has worked as a Programmer Analyst at the University of Alberta since 2002 and is comfortable programming in Perl, Java, C, C++, Visual Basic, and MySQL. He developed GelScape, a web-based gel viewing and annotation system.

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This project is supported by Genome Alberta and Genome Canada, a not-for-profit organization that is leading Canada's national strategy on genomics with $600 million in funding from the federal government.